This book provides up-to-date, practical information on functional mapping in order to assist neurosurgeons responsible for safely removing lesions in and around eloquent cortex one of the greatest challenges in neurosurgery.  The roles of pre- and intraoperative mapping techniques are clearly explained, highlighting the advantages and limitations of each tool available to the neurosurgeon. The inclusion of treatment algorithms for applications in specific clinical circumstances ensures that the book will serve as a clear guide to this most complex of neurosurgical problems. To further assist the reader, instructive clinical case examples, accompanied by intraoperative photos and other illustrative material, help to explain the applications of functional mapping of eloquent cortex in different pathologies. Practitioners will find the book to be a ready guide to navigation of the practical decisions commonly faced when operating in eloquent cortex.

Richard William Byrne, MD, has been Professor of Neurosurgery at Rush Medical College, Chicago, Ill., since 2008 and in 2013 was appointed The Roger C. Bone, MD, Presidential Professor of Rush University. He is Medical Director of Rush University Neurosurgery and Chairman of the Department of Neurosurgery at Rush Medical College. Dr. Byrne is certified by the American Board of Neurological Surgery. He has served as an officer in various medical societies and on national committees and is a member of the Board of Directors of the CNS Foundation. Since 2012 he has been Treasurer and Executive Committee member of the Neurosurgical Society of America. In 2014 he received the Gary Lichtenstein Humanitarian Award from Voices Against Brain Cancer. Dr. Byrne has conducted extensive research on diverse topics and is the author of more than 80 articles in peer-reviewed journals as well as over 20 book chapters. He is a member of the editorial board for Surgical Neurology International anduntil 2013 was a member of the editorial board of AANS Neurosurgeon. In 2014 he was a guest editor for Seminars in Oncology, and he is also a reviewer for many other journals.

Historical Perspective on the Development of Cerebral Localization, Cerebral Cortical Motor Stimulation, and Sensory Evoked Potentials.- Anatomy of Important Functioning Cortex.- Mapping Eloquent Brain with functional MRI and DTI.- Intra-Operative Cortical Stimulation Mapping. Technique and Limitations.- Anesthetic Considerations in Cortical Mapping and Awake Surgery.- Mapping Cortical Function with Event-Related Electrocorticography.- Mapping of Eloquent Cortex in Focal Epilepsy with Intracranial Electrodes.- Somatosensory and Motor Evoked Potentials in Surgery of Eloquent Cortex Under General Anesthesia: Advantages and Limitations.- Cortical Mapping with Transcranial Magnetic Stimulation.- Practical application of Pre-Operative and Intra-Operative Cortical Mapping in Surgery.- Epilepsy Surgery in Eloquent Cortex.- White Matter Tracts.- Intraoperative Cortical Stimulation and the Value of Negative Mapping.