This book covers important topics such as the dynamic structure and function of the 26S proteasome, the DNA replication machine: structure and dynamic function and the structural organization and protein-protein interactions in the human adenovirus capsid, to mention but a few.The 18 chapters included here, written by experts in their specific field, are at the forefront of scientific knowledge. The impressive integration of structural data from X-ray crystallography with that from cryo-electron microscopy is apparent throughout the book. In addition, functional aspects are also given a high priority. Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Dr J. Robin Harris is a retired biochemist with specialism in macromolecular electron microscopy, now based in the UK. He is the long-standing Series Editor of Subcellular Biochemistry. He is an Honorary Professor of the University of Mainz.Dr Jon Marles-Wright is a Senior Lecturer in the School of Natural and Environmental Sciences at Newcastle University. He has broad interest and experience in biomolecular X-ray crystallography and cryoelectron microscopy.